Medchemexpress LLC N-(Amino-PEG1)-N-bis(PEG2-propargyl) | 2100306-47-4 | 98.0% | 356.46 | 50 MG

Supplier:  Medchemexpress LLC HY14008650MG

N-(Amino-PEG1)-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. This compound acts as a click chemistry reagent, featuring an alkyne group that can engage in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups. PROTACs themselves consist of two different ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets a specific protein. PROTACs function by leveraging the intracellular ubiquitin-proteasome system for selective degradation of target proteins.

• Utilized in the synthesis of PROTACs
• Acts as a click chemistry reagent
• Features an alkyne group for copper-catalyzed azide-alkyne cycloaddition
• Engages with molecules containing azide groups
• PROTACs leverage the intracellular ubiquitin-proteasome system
• Enables selective degradation of target proteins

Catalog No. 50-003-49854