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Medchemexpress LLC N-(Amino-PEG1)-N-bis(PEG2-propargyl) | 2100306-47-4 | 98.0% | 356.46 | 50 MG
SDP

Catalog No. 5000349854
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N-(Amino-PEG1)-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. This compound acts as a click chemistry reagent, featuring an alkyne group that can engage in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups. PROTACs themselves consist of two different ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets a specific protein. PROTACs function by leveraging the intracellular ubiquitin-proteasome system for selective degradation of target proteins.

  • Utilized in the synthesis of PROTACs
  • Acts as a click chemistry reagent
  • Features an alkyne group for copper-catalyzed azide-alkyne cycloaddition
  • Engages with molecules containing azide groups
  • PROTACs leverage the intracellular ubiquitin-proteasome system
  • Enables selective degradation of target proteins

Catalog No. 50-003-49854 Supplier Medchemexpress LLC Supplier No. HY14008650MG
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N-(Amino-PEG1)-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. This compound acts as a click chemistry reagent, featuring an alkyne group that can engage in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups. PROTACs themselves consist of two different ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets a specific protein. PROTACs function by leveraging the intracellular ubiquitin-proteasome system for selective degradation of target proteins.

  • Utilized in the synthesis of PROTACs
  • Acts as a click chemistry reagent
  • Features an alkyne group for copper-catalyzed azide-alkyne cycloaddition
  • Engages with molecules containing azide groups
  • PROTACs leverage the intracellular ubiquitin-proteasome system
  • Enables selective degradation of target proteins

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