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Medchemexpress LLC N-(Amino-PEG4)-N-bis(PEG4-Boc) | 2093153-97-8 | C40H80N2O16 | 25 MG
SDP

Catalog No. 5000357389
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N-(Amino-PEG4)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs and advanced bioconjugation applications. This heterotrifunctional, branched polyethylene glycol (PEG) linker facilitates sequential and controlled conjugation strategies.

  • PROTACs degrade target proteins by exploiting the intracellular ubiquitin-proteasome system
  • Contains a single primary amine on one PEG arm and two Boc-protected amines on the other two arms
  • Enables initial conjugation via the primary amine to a biomolecule
  • Boc protecting groups can be removed to expose additional primary amines for conjugating a second molecule
  • PEG spacers enhance solubility, stability, and pharmacokinetic properties of the conjugate
  • Reduces steric hindrance in resulting biomolecular constructs

Catalog No. 50-003-57389 Supplier Medchemexpress LLC Supplier No. 25MGHY140255
May include imposed supplier surcharges.
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N-(Amino-PEG4)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs and advanced bioconjugation applications. This heterotrifunctional, branched polyethylene glycol (PEG) linker facilitates sequential and controlled conjugation strategies.

  • PROTACs degrade target proteins by exploiting the intracellular ubiquitin-proteasome system
  • Contains a single primary amine on one PEG arm and two Boc-protected amines on the other two arms
  • Enables initial conjugation via the primary amine to a biomolecule
  • Boc protecting groups can be removed to expose additional primary amines for conjugating a second molecule
  • PEG spacers enhance solubility, stability, and pharmacokinetic properties of the conjugate
  • Reduces steric hindrance in resulting biomolecular constructs

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