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Medchemexpress LLC N-Arachidonyl maleimide | 876305-42-9 | 98.3% | 369.54 | 1 ML
SDP

Supplier:  Medchemexpress LLC HY13656210MM/1ML

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N-Arachidonyl maleimide is a potent, irreversible inhibitor of monoacylglycerol lipase (MAGL) with an IC50 value of 140 nM. It modulates the effects of 2-arachidonyl glycerol (2-AG) by increasing its endogenous levels in the brain and preventing cerebellar membrane-mediated degradation.

  • Potent and irreversible monoacylglycerol lipase (MAGL) inhibitor
  • Modulates effects of 2-arachidonyl glycerol (2-AG)
  • Increases endogenous levels of 2-AG in the brain
  • Prevents cerebellar membrane-mediated degradation of 2-AG
  • Induces hypothermia, antinociception, and catalepsy in vivo when combined with 2-AG

Catalog No. 50-003-51938


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