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Medchemexpress LLC N-Arachidonyl maleimide | 876305-42-9 | 98.31% | 369.54 | 10 MG
SDP

Supplier:  Medchemexpress LLC 10MGHY136562

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N-Arachidonyl maleimide is a potent, irreversible inhibitor of monoacylglycerol lipase (MAGL) with an IC50 value of 140 nM. It modulates the effects of 2-arachidonyl glycerol (2-AG) by increasing endogenous levels of 2-AG in the brain and preventing cerebellar membrane-mediated degradation of 2-AG.

  • Potent, irreversible inhibitor of monoacylglycerol lipase (MAGL)
  • Modulates effects of 2-arachidonyl glycerol (2-AG)
  • Increases endogenous levels of 2-AG in the brain
  • Prevents cerebellar membrane-mediated degradation of 2-AG
  • Produces hypothermia, inhibition of locomotor activity, antinociception, and catalepsy in vivo

Catalog No. 50-003-65537


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