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Medchemexpress LLC N-(Azido-PEG3)-N-(PEG2-amine)-PEG3-acid | 2183440-70-0 | 99.6% | C24H47N5O11 | 25 MG
Supplier: Medchemexpress LLC 25MGHY140247
N-(Azido-PEG3)-N-(PEG2-amine)-PEG3-acid is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. It acts as a versatile click chemistry reagent, facilitating selective degradation of target proteins via the intracellular ubiquitin-proteasome system.
- Contains an Azide group
- Participates in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules possessing Alkyne groups
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups
- Functions as a PROTAC linker
- Utilized in PROTAC synthesis
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