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Medchemexpress LLC N-(Azido-PEG4)-N-Boc-PEG4-NHS ester | 2112731-96-9 | ≥97.0% | 25 MG
Supplier: Medchemexpress LLC 25MGHY130312
N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a PEG-based PROTAC linker, primarily utilized in the synthesis of PROTACs. It functions as a versatile click chemistry reagent due to its terminal azide group. This enables it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN group-containing molecules.
- PEG-based PROTAC linker with a terminal azide group
- Used in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne groups
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups
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