N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester, 95%

Description

CAS: 286961-14-6 | C16H28BNO4 | 309.21 g/mol

Reagent used for suzuki-Miyaura cross-coupling using palladium phosphine catalyst, palladium-catalyzed ligand-controlled regioselective Suzuki coupling, wrenchnolol derivative optimized for gene activation in cells. Also used in Preparation of several enzymatic inhibitors and receptor ligands, orally active anaplastic lymphoma kinase inhibitors and oxazolecarboxamides as diacylglycerol acyltransferase-1 inhibitors for treatment of obesity and diabetes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Reagent used for suzuki-Miyaura cross-coupling using palladium phosphine catalyst, palladium-catalyzed ligand-controlled regioselective Suzuki coupling, wrenchnolol derivative optimized for gene activation in cells. Also used in Preparation of several enzymatic inhibitors and receptor ligands, orally active anaplastic lymphoma kinase inhibitors and oxazolecarboxamides as diacylglycerol acyltransferase-1 inhibitors for treatment of obesity and diabetes.

Solubility
Soluble in most organic solvents. Insoluble in water.

Notes
Store in cool, dry place in tightly closed container. With adequate ventilation. Store away from oxidizing agent.

Specifications

Chemical Identifiers

• CAS: 286961-14-6
• Molecular Formula: C16H28BNO4
• Molecular Weight (g/mol): 309.21
• MDL Number: MFCD03840345
• InChI Key: VVDCRJGWILREQH-UHFFFAOYSA-N
• Synonym: n-boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester, tert-butyl 4-4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl-5,6-dihydropyridine-1 2h-carboxylate, 1-n-boc-4-4,4,5,5-tetramethyl-1,3,2 dioxaborolan-2-yl-3,6-dihydro-2h-pyridine, n-boc-1,2,3,6-tetrahydropyridine-4-boronic acid pinacol ester, tert-butyl 4-4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl-3,6-dihydro-2h-pyridine-1-carboxylate, tert-butyl 5,6-dihydro-4-4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl pyridine-1 2h-carboxylate, 3,6-dihydro-2h-pyridine-1-n-boc-4-boronic acid pinacol ester, n-tert-butoxycarbonyl-1,2,3,6-tetrahydropyridine-4-boronic acid pinacol ester, 1-boc-4-4,4,5,5-tetramethyl-1,3,2 dioxaborolan-2-yl-3,6-dihydro-2h-pyridine, tert-butyl 4-tetramethyl-1,3,2-dioxaborolan-2-yl-1,2,3,6-tetrahydropyridine-1-carboxylate
• PubChem CID: 4642098
• IUPAC Name: tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-2H-pyridine-1-carboxylate
• SMILES: CC(C)(C)OC(=O)N1CCC(=CC1)B1OC(C)(C)C(C)(C)O1

• Quantity: 25 g
• Solubility Information: Soluble in most organic solvents. Insoluble in water.
• Formula Weight: 327.23
• Percent Purity: 95%
• Physical Form: Solid
• Chemical Name or Material: N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester

Safety and Handling

TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only