N-Boc-L-proline, 99%, Thermo Scientific Chemicals

Description

N-Boc-L-proline is used as an intermediate in organic synthesis. It is also used to prepare daclatasvir, which inhibits the hepatitis C virus (HCV) non-structural 5A (NS5A) protein. Further, it is used as a drug in the treatment of hepatitis C virus (HCV).

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
N-Boc-L-proline is used as an intermediate in organic synthesis. It is also used to prepare daclatasvir, which inhibits the hepatitis C virus (HCV) non-structural 5A (NS5A) protein. Further, it is used as a drug in the treatment of hepatitis C virus (HCV).

Solubility
Soluble in acetic acid.

Notes
Moisture and light sensitive. Incompatible with strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 15761-39-4
• Molecular Formula: C10H17NO4
• Molecular Weight (g/mol): 215.249
• MDL Number: MFCD00037324
• InChI Key: ZQEBQGAAWMOMAI-ZETCQYMHSA-N
• Synonym: boc-l-proline, boc-pro-oh, n-boc-l-proline, n-tert-butoxycarbonyl-l-proline, boc-l-pro-oh, s-1-tert-butoxycarbonyl pyrrolidine-2-carboxylic acid, n-tert-butyloxycarbonyl-l-proline, tert-butoxycarbonyl-l-proline, 1-tert-butoxycarbonyl-l-proline, boc-l-pro
• PubChem CID: 85083
• IUPAC Name: (2S)-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid
• SMILES: CC(C)(C)OC(=O)N1CCCC1C(=O)O

• Melting Point: 132°C to 136°C
• Quantity: 5 g
• Beilstein: 15828
• Solubility Information: Soluble in acetic acid.
• Optical Rotation: −61° (c=1 in Acetic Acid)
• Formula Weight: 215.25
• Percent Purity: 99%
• Chemical Name or Material: N-Boc-L-proline

Safety and Handling

EINECSNumber	239-848-3
TSCA	Yes
Recommended Storage	Keep cold

SDS

RUO – Research Use Only