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Medchemexpress LLC N-(cyanomethyl)-N-methyl-2-oxo-2-[4-(7-oxo-6,7,8,9-tetrahydro-5H-benzoannulen-5-yl)phenoxy] | 2226521-65-7 | MFCD31630713 | 99.6% | 428.49 g·mol⁻1 | C24H24N6O2 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY10204650MG

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FM-381 is a potent, covalent reversible inhibitor selective for Janus kinase 3 (JAK3). It demonstrates sub-nanomolar potency (IC50 = 127 pM) and high selectivity versus other JAK family members, making it a useful research tool for probing JAK/STAT signaling in biochemical and cellular studies. Supplied as a high-purity material for laboratory use.

  • High potency for JAK3 (IC50 = 127 pM).
  • Covalent reversible mode of inhibition.
  • Marked selectivity versus JAK1, JAK2, and TYK2.
  • Suitable for biochemical and cellular assays.
  • Provided as a high-purity research chemical.

Catalog No. 50-002-47345


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