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Medchemexpress LLC N-cycloheptyl-6,7-dimethoxy-2-(4-piperidin-1-ylpiperidin-1-yl)quinazolin-4-amine | 864289-85-0 | 100.0% | 467.65 g/mol | C27H41N5O2 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY10336450MG

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C-021 is a small-molecule antagonist of CC chemokine receptor 4 (CCR4) developed for research applications; it blocks CCR4-mediated signaling and functional chemotaxis, with low-nanomolar activity in binding and cell-based assays.

  • Potent CCR4 antagonist with low-nanomolar binding activity.
  • Prevents CCL22-derived [35S]GTPγS binding to CCR4 (IC50 18 nM) and inhibits functional chemotaxis (human 140 nM, mouse 39 nM).
  • Molecular formula C27H41N5O2; molecular weight 467.65 g/mol.
  • High purity (~99.95%).
  • Solid form with recommended storage: powder -20°C (long term) or 4°C (short term); in solvent store at -80°C.
  • Intended for research use only; not for human use.

Catalog No. 50-002-44577


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