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Medchemexpress LLC N-DBCO-N-bis(PEG2-C2-acid) | 2110449-00-6 | 96.7% | C33H40N2O10 | 25 MG
Supplier: Medchemexpress LLC 25MGHY140543
N-DBCO-N-bis(PEG2-C2-acid) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing a DBCO group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules possessing Azide groups. PROTACs comprise two distinct ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets a specific protein, facilitating the selective degradation of target proteins through the intracellular ubiquitin-proteasome system.
- Peg-based protac linker
- Click chemistry reagent
- Facilitates strain-promoted alkyne-azide cycloaddition (SPAAC)
- Enables selective degradation of target proteins
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