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Medchemexpress LLC N-Descyclopropanecarbaldehyde Olaparib | 763111-47-3 | 98.7% | C20H19FN4O2 | 1 ML

Supplier: Medchemexpress LLC HY7570610MM/1ML
N-Descyclopropanecarbaldehyde Olaparib is an analogue of Olaparib containing a DOTA moiety. It acts as a PARP inhibitor and is utilized in the synthesis of novel dual EGFR and PARP PROTACs. This compound can be radiolabeled with F-18 or a fluorophore for positron emission tomography (PET) or optical imaging in various tumor types.
- Acts as a PARP inhibitor
- Used for the synthesis of novel dual EGFR and PARP PROTACs
- Can be radiolabeled for PET or optical imaging in various tumor types
- Exhibits antiproliferative activity against BRCA deficient human DLD1 cells (EC50: 0.2 μM)
- Inhibits human HeLa cell derived PARP (IC50: < 20 nM)
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