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Cayman Chemical N-desmethyl ImatInIb 10mg

Supplier: Cayman Chemical 1694710 MG
A major active metabolite of imatinib; formed through demethylation of imatinib by CYP3A4; has the same in vitro potency at Bcr-ABL kinase as imatinib (IC50 = 38 nM for both) but is only present in plasma at 10-15% of the levels of imatinib
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