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Medchemexpress LLC N-Desmethyltamoxifen hydrochloride | 15917-65-4 | 99.6% | 1 ML
SDP

Catalog No. 5000338754
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N-Desmethyltamoxifen hydrochloride is the primary metabolite of tamoxifen in humans. It acts as a poor antiestrogen and is a more potent protein kinase C (PKC) inhibitor than Tamoxifen, exhibiting a ten-fold greater potency. Additionally, N-Desmethyltamoxifen hydrochloride effectively regulates ceramide metabolism in human AML cells, by limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation.

  • Primary metabolite of tamoxifen in humans
  • Potent protein kinase C (PKC) inhibitor
  • Regulates ceramide metabolism in human AML cells
  • Shows inhibitory effect on various glioma lines
  • Inhibits the growth of human mammary carcinoma cells
  • Formed by CYP3A4/5-mediated catalysis of tamoxifen

Catalog No. 50-003-38754 Supplier Medchemexpress LLC Supplier No. HY129099A10MM/1ML
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N-Desmethyltamoxifen hydrochloride is the primary metabolite of tamoxifen in humans. It acts as a poor antiestrogen and is a more potent protein kinase C (PKC) inhibitor than Tamoxifen, exhibiting a ten-fold greater potency. Additionally, N-Desmethyltamoxifen hydrochloride effectively regulates ceramide metabolism in human AML cells, by limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation.

  • Primary metabolite of tamoxifen in humans
  • Potent protein kinase C (PKC) inhibitor
  • Regulates ceramide metabolism in human AML cells
  • Shows inhibitory effect on various glioma lines
  • Inhibits the growth of human mammary carcinoma cells
  • Formed by CYP3A4/5-mediated catalysis of tamoxifen

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