Medchemexpress LLC N-dibenzofuran-3-yl-5-nitrofuran-2-carboxamide | 329198-87-0 | 99.5% | 322.27 g/mol | C17H10N2O5 | 250MG

Supplier:  Medchemexpress LLC HY123963250MG

C-178 is a potent, selective, covalent small-molecule inhibitor of the Stimulator of Interferon Genes (STING). It covalently modifies Cys91 on mouse STING, blocking palmitoylation and downstream signaling; the compound is active in mouse models but shows little to no activity against human STING. Supplied as a research-grade compound for preclinical studies; not for human or veterinary use.

• Covalent inhibitor of STING that binds Cys91.
• Selective activity in mouse STING assays, not active on human STING.
• Molecular formula C17H10N2O5 and molecular weight 322.27 g/mol.
• High purity, typically ≥99% by HPLC.
• Appearance: yellow to orange solid; soluble in DMSO.
• Mechanism blocks STING palmitoylation and downstream signaling events.
• Intended for research use only; not for clinical use.

Catalog No. 50-002-35395