Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC N-Ethylmaleimide | 128-53-0 | 200 MG
Supplier: Medchemexpress LLC HYD0843200MG
N-Ethylmaleimide (NEM) is derived from maleic acid and can alkylate free sulfhydryl groups. It acts as an irreversible cysteine protease inhibitor. NEM specifically inhibits phosphate transport in mitochondria and inhibits prolyl endopeptidase with an IC50 value of 6.3 μM. It can be used to modify cysteine residues in proteins and peptides, and is also a deubiquitinating enzyme inhibitor.
- Irreversible cysteine protease inhibitor
- Specifically inhibits phosphate transport in mitochondria
- Inhibits prolyl endopeptidase (IC50 value of 6.3 μM)
- Modifies cysteine residues in proteins and peptides
- Deubiquitinating enzyme inhibitor
- Inhibits Akt phosphorylation
- Affects pro-caspase-3 conversion
- Promotes vascular smooth muscle cell apoptosis
- Affects PP2A activity and ROS production
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?