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Medchemexpress LLC N'-Hexadecylthiophene-2-carbohydrazide | 2374313-54-7 | 99.43% | 10 MG
Supplier: Medchemexpress LLC HY12891810MG
SIS17 is a mammalian histone deacetylase 11 (HDAC 11) inhibitor with an IC50 value of 0.83 μM. It inhibits the demyristoylation of serine hydroxymethyltransferase 2, a substrate of HDAC 11, but does not inhibit other HDACs. This product is for research use only.
- IC50 value of 0.83 μM for HDAC11
- Inhibits demyristoylation of serine hydroxymethyltransferase 2
- Does not inhibit other HDACs
- Increases fatty acylation level of SHMT2 in MCF7 cells
- Demonstrates synergistic cytotoxicity with Oxaliplatin in K562 cells
- White to off-white solid appearance
- Purity of 99.43%
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