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Medchemexpress LLC N-hydroxy-4-(3-(pyridin-2-yl)phenyl)benzamide | 2151853-97-1 | MFCD32063565 | 99.8% | 293.32 g/mol | C17H15N3O2 | 100MG
Supplier: Medchemexpress LLC HY123976100MG
MPT0G211 is a potent, orally active, selective histone deacetylase 6 (HDAC6) inhibitor provided for research use. It exhibits >1,000-fold selectivity for HDAC6, a reported IC50 of 0.291 nM, and is reported to penetrate the blood-brain barrier. Preclinical studies report modulation of tau phosphorylation, improvement of cognitive deficits in Alzheimer disease models, and anti-metastatic, neuroprotective, and anticancer activities.
- Potent HDAC6 inhibition (IC50 = 0.291 nM).
- Greater than 1,000-fold selectivity for HDAC6 over other isoforms.
- Reported blood-brain barrier penetration for central nervous system studies.
- Demonstrated activity in Alzheimer disease and anticancer models.
- High chemical purity (reported 99.8%).
- Available in multiple solid and solution pack sizes for flexible use.
- For research use only; not for human or veterinary use.
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