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Sigma Aldrich N-Hydroxysuccinimide ester-poly(ethylene glycol)-b-poly(D,L-»lactide)

Catalog No. 909874100MG Shop All MilliporeSigma Sigma Organic Chemistry Products
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90-987-4100MG 100 mg
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Description

MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.

N-Hydroxysuccinimide ester-poly(ethylene glycol)-b-poly(D,L lactide) is a functionalized, amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PLA block. These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). The NHS functional group on the PEG chain enables rapid and facile surface functionalization, allowing for these materials to be used in applications such as targeted drug delivery.

Specifications

Linear Formula HO(C3H4O2)m(C2H4O)nC7H8NO4
Quantity 100 mg
Synonym NHS ester PEG-PDLA; NHS ester PEG-PLA; NHS-PEG-PDLA; NHS-PEG-PLA
Molecular Weight (g/mol) 5000
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