N-Hydroxysulfosuccinimide sodium salt, 97%

Description

CAS: 106627-54-7 | C4H4NNaO6S | 217.127 g/mol

N-Hydroxysulfosuccinimide sodium salt is used as crosslinking agents for preparing hydrophilic active esters. It is also used to activate carboxylic acids to the more reactive succinimidyl esters for coupling, biotinylation and conjugation with fluorophores. Further, it acts as a hydrophilic ligand and also used in covalently binding proteins to carboxyl containing beads, resins, other nanoparticles. It is involved in the conversion of carboxyl groups to primary amine-reactive sulfo-NHS esters.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
N-Hydroxysulfosuccinimide sodium salt is used as crosslinking agents for preparing hydrophilic active esters. It is also used to activate carboxylic acids to the more reactive succinimidyl esters for coupling, biotinylation and conjugation with fluorophores. Further, it acts as a hydrophilic ligand and also used in covalently binding proteins to carboxyl containing beads, resins, other nanoparticles. It is involved in the conversion of carboxyl groups to primary amine-reactive sulfo-NHS esters.

Solubility
Soluble in methanol and water.

Notes
Store in a cool place. Moisture sensitive. Incompatible with strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 106627-54-7
• Molecular Formula: C4H4NNaO6S
• Molecular Weight (g/mol): 217.127
• MDL Number: MFCD00043100
• InChI Key: RPENMORRBUTCPR-UHFFFAOYSA-M
• Synonym: n-hydroxysulfosuccinimide sodium salt, sulfo-nhs, sodium 1-hydroxy-2,5-dioxopyrrolidine-3-sulfonate, n-hydroxysulfosuccinimidesodiumsalt, 3-pyrrolidinesulfonic acid, 1-hydroxy-2,5-dioxo-, monosodium salt, sodium 1-hydroxy-2,5-dioxo-pyrrolidine-3-sulfonate, n-hydroxusulfosuccinimide sodium, n-hydroxy-2-sodiosulfo succinimide, n-hydroxysulfosuccinimide,sodium salt, n-hydroxusulfosuccinimide sodium salt
• PubChem CID: 3520574
• IUPAC Name: sodium;1-hydroxy-2,5-dioxopyrrolidine-3-sulfonate
• SMILES: C1C(C(=O)N(C1=O)O)S(=O)(=O)[O-].[Na+]

• Melting Point: 250°C
• Quantity: 250 mg
• Beilstein: 6359129
• Solubility Information: Soluble in methanol and water.
• Formula Weight: 217.13
• Percent Purity: 97%
• Chemical Name or Material: N-Hydroxysulfosuccinimide sodium salt

Safety and Handling

Hazard Category	H315-H319-H335
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only