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Medchemexpress LLC N-methyl-L-alanyl-(2S)-2-cyclohexylglycyl-N-(4-phenyl-thiadiazol-5-yl)-L-prolinamide | 873652-48-3 | MFCD26142660 | 99.7% | 498.64 | C25H34N6O3S | 5 MG
SDP

Catalog No. 5000222122
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GDC-0152 is a small-molecule inhibitor of inhibitor of apoptosis proteins (IAPs) used in research to probe apoptosis signaling. It selectively binds BIR domains of XIAP, cIAP1, cIAP2, and ML-IAP with low-nanomolar affinity and is supplied as a stable powder for laboratory use.

  • Pan-IAP inhibitor targeting BIR domains of XIAP, cIAP1, cIAP2, and ML-IAP.
  • Low-nanomolar Ki values: 28 nM (XIAP), 17 nM (cIAP1), 43 nM (cIAP2), 14 nM (ML-IAP).
  • Soluble in DMSO and ethanol at 50 mg/mL; ultrasonic assistance may be required.
  • Powder storage recommended at -20°C for long-term stability; in-solution storage at -80°C where applicable.
  • For research use only; not for clinical applications.

Catalog No. 50-002-22122 Supplier Medchemexpress LLC Supplier No. HY136385MG
May include imposed supplier surcharges.
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GDC-0152 is a small-molecule inhibitor of inhibitor of apoptosis proteins (IAPs) used in research to probe apoptosis signaling. It selectively binds BIR domains of XIAP, cIAP1, cIAP2, and ML-IAP with low-nanomolar affinity and is supplied as a stable powder for laboratory use.

  • Pan-IAP inhibitor targeting BIR domains of XIAP, cIAP1, cIAP2, and ML-IAP.
  • Low-nanomolar Ki values: 28 nM (XIAP), 17 nM (cIAP1), 43 nM (cIAP2), 14 nM (ML-IAP).
  • Soluble in DMSO and ethanol at 50 mg/mL; ultrasonic assistance may be required.
  • Powder storage recommended at -20°C for long-term stability; in-solution storage at -80°C where applicable.
  • For research use only; not for clinical applications.

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