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Medchemexpress LLC N-methylmethanesulfonamide chromanol derivative | 223749-46-0 | MFCD12756323 | 100.0% | 411.44 g·mol⁻¹ | C17H24F3NO5S | 50 MG
Supplier: Medchemexpress LLC HY10636950MG
HMR 1556 is a chromanol-derived research compound that potently and selectively blocks the slowly activating delayed rectifier potassium current (IKs). It is used as a pharmacological tool in cardiac electrophysiology and pharmacology to probe IKs-mediated repolarization in vitro and in vivo. Reported IC50 values include 10.5 nM (canine left ventricular myocytes) and 34 nM (guinea pig left ventricular myocytes).
- Potent IKs blockade at low-nanomolar concentrations.
- Selective for IKs with limited off-target activity at pharmacologically relevant doses.
- Suitable for in vitro and in vivo electrophysiology and pharmacology studies.
- High-purity solid form, soluble in DMSO for stock solutions.
- Documented solubility and storage conditions for reliable experimental use.
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