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Medchemexpress LLC N,N-Dimethyl-3-(5-(2-(methylsulfonyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-indol-1-yl)propan-1-amine hydrochloride | 97.0% | C20H24ClN5O2S | 50 MG
SDP

Supplier:  Medchemexpress LLC HY141703A50MG

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DC-BPi-11 hydrochloride is an inhibitor of bromodomain PHD finger transcription factor (BPTF), with an IC50 value of 698 nM. It demonstrates remarkable inhibition against leukemia cell proliferation and is suitable for laboratory research. The compound shows minimal effects on normal cells.

  • Inhibits BPTF with an IC50 value of 698 nM
  • Shows remarkable inhibition against leukemia cell proliferation
  • Inhibits BPTF in human leukemia MV-4-11 cells with an EC50 value of 120 nM
  • Significantly inhibits the proliferation of human leukemia MV-4-11 cells (IC50=0.89 μM)
  • Decreases downstream oncogene expression at concentrations between 2.5-20 μM
  • Dose-dependently decreases c-Myc protein level
  • Shows minimal effects on normal cells, indicating its safety

Catalog No. 50-003-54172


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