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Medchemexpress LLC N,N'-Dinitrosopiperazine | 140-79-4 | 99.9% | 144.13 | 100 MG
Supplier: Medchemexpress LLC HY136433100MG
N,N'-Dinitrosopiperazine (DNP) is identified as a carcinogen with specificity for nasopharyngeal epithelium, facilitating nasopharyngeal carcinoma (NPC) metastasis. It regulates multiple signaling pathways through protein phosphorylation, including LYRIC at serine 568.
- Specific carcinogen for nasopharyngeal epithelium
- Facilitates NPC metastasis
- Regulates multiple signaling pathways through protein phosphorylation
- Induces cell invasion and motility in a dose-dependent manner in vitro
- Increases expression of phospho-LYRIC s568 and LYRIC in CNE1 cells
- Promotes NPC metastasis in vivo by inhibiting cell motility and invasion
- Induces LYRIC phosphorylation at serine 568 in vivo
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