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Medchemexpress LLC N,N'-trans-1,4-cyclohexanediylbis[2-(4-chlorophenoxy)acetamide] | 1597403-47-8 | MFCD27952932 | 99.5% | 451.34 g/mol | C22H24Cl2N2O4 | 10MM 1ML
SDP

Supplier:  Medchemexpress LLC HY1249510MM 1ML

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ISRIB (trans-isomer) is a small-molecule inhibitor of the integrated stress response that potently inhibits PERK and reverses eIF2α phosphorylation. It is supplied as a 10 mM solution in DMSO or as solid quantities for use in biochemical and cellular assays; reported purity is 99.49% and molecular weight 451.34 g/mol.

  • Potent PERK inhibition with reported IC50 of 5 nM.
  • Reverses eIF2α phosphorylation in cellular assays.
  • Available as 10 mM solution in DMSO and multiple solid sizes.
  • High purity suitable for research applications.
  • Molecular weight 451.34 g/mol and formula C22H24Cl2N2O4.
  • Useful for biochemical and cell-based studies of the integrated stress response.

Catalog No. 50-002-35622


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