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Bachem N-o-Hydroxy-L-norarginine

Supplier: Bachem 4027934.0050
N-o-Hydroxy-L-norarginine Acetate, 189302-40-7, C5H12N4O3, Mr 176.18, 50mg. nor-NOHA, L-2-Amino-4-(2'-hydroxyguanidino)-butyric acid, H-Nar(OH)-OH. N-o-Hydroxy-L-norarginine (or N-o-Hydroxy-nor-L-arginine) is a most potent reversible inhibitor of arginase. At pH 7.4 nor-NOHA inhibited the rat liver arginase-dependent hydrolysis of H-Arg-OH with an EC50 = 2 ± 0.5 uM and the arginase activity of mouse macrophages with an EC50 value of 50 ± 10 uM.
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