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Medchemexpress LLC N-(p-Coumaroyl) Serotonin | 68573-24-0 | 99.0% | 25 MG

Supplier: Medchemexpress LLC 25MGHY129440
N-(p-Coumaroyl) Serotonin is a selective inhibitor of PDGFRβ, ERK1/2, and caspase-8 with antioxidant, anti-atherosclerotic, and anti-inflammatory properties. It inhibits glioblastoma cells (U251MG, T98G) and normal fibroblasts. This compound inhibits PDGF signaling by reducing receptor phosphorylation, blocks Ca2+ influx, and induces apoptosis by activating caspase-8. It may improve atherosclerosis and aortic wall enlargement, and is also used in the study of glioblastoma.
- Selective inhibitor of PDGFRβ, ERK1/2, and caspase-8
- Possesses antioxidant, anti-atherosclerotic, and anti-inflammatory properties
- Inhibits glioblastoma cell growth
- Inhibits PDGF signaling by reducing receptor phosphorylation
- Blocks Ca2+ influx and induces apoptosis
- May improve atherosclerosis and aortic wall enlargement
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