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Medchemexpress LLC N-piperidine Ibrutinib hydrochloride | 2231747-18-3 | 98.1% | 1 ML
Supplier: Medchemexpress LLC HY13098310MM/1ML
N-piperidine Ibrutinib hydrochloride is a reversible Ibrutinib derivative and a potent BTK inhibitor. It demonstrates high efficacy with IC50s of 51.0 nM for WT BTK and 30.7 nM for C481S BTK. This compound serves as a valuable BTK ligand in the synthesis of various PROTACs, including potent PROTAC BTK degraders.
- Potent BTK inhibitor
- Reversible Ibrutinib derivative
- Useful as a BTK ligand for PROTAC synthesis
- Effective against both WT BTK and C481S BTK
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