Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC N-Propargylglycine | 58160-95-5 | 99.7% | C5H7NO2 | 10MM/1ML
Supplier: Medchemexpress LLC HY14203510MM/1ML
N-Propargylglycine is a brain-penetrant, orally active PRODH inhibitor. It irreversibly inhibits proline and 4-hydroxyproline catabolism by covalently modifying enzyme-bound FAD and active site lysine. This compound induces UPRmt, upregulates mitochondrial chaperones, and enhances mitochondrial proteostasis. It also stimulates neural processes, increases brain proline levels, and normalizes Huntington's disease transcriptomes. Additionally, N-Propargylglycine reduces hyperoxaluria and prevents calcium oxalate stone formation.
- Brain-penetrant and orally active PRODH inhibitor
- Irreversible inhibition of proline catabolism
- Enhances mitochondrial proteostasis
- Stimulates neural processes; increases brain proline
- Normalizes Huntington's disease transcriptomes
- Reduces hyperoxaluria; prevents calcium oxalate stones
- Research applications include breast cancer and neurodegenerative disorders
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?