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Medchemexpress LLC N-succinimidyl 3-(2-pyridyldithio)propionate | 68181-17-9 | MFCD00009636 | 99.1% | 312.37 g/mol | C12H12N2O4S2 | 250 MG
SDP

Supplier:  Medchemexpress LLC HY100216250MG

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SPDP is a short-chain, heterobifunctional crosslinker (N-succinimidyl 3-(2-pyridyldithio)propionate) that contains an NHS ester and a pyridyldithiol group. It enables formation of a cleavable disulfide linkage between primary amines and sulfhydryls, making it suitable for reversible bioconjugation, protein labeling, and linker applications requiring reduction-sensitive release.

  • Enables amine-to-sulfhydryl conjugation via NHS ester and pyridyldithiol.
  • Forms cleavable disulfide bonds reducible by intracellular glutathione.
  • Short spacer arm minimizes steric interference in conjugates.
  • Suitable for antibody-drug conjugates and reversible protein labeling.
  • Provided as a high-purity solid for biochemical reactions.

Catalog No. 50-002-15604


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