N-tert-Butyl-alpha-phenylnitrone, 97%

Description

CAS: 3376-24-7 | C11H15NO | 177.247 g/mol

N-tert-Butyl-a-phenylnitrone is a commonly-used free radical trap. It contains radical scavenging activity and an ability to inhibit Cox-2 (cyclooxygenase-2). N-tert-Butyl-a-phenylnitrone is an antioxidant that has been shown to act as a protective agent in several experimental models of neurodegenerative disorders. N-tert-Butyl-a-phenylnitrone inhibits lipid peroxidation in rat liver microsomes. It also prevents the induction of inducible nitric oxide synthase (iNOS) by reactive oxygen species.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
N-tert-Butyl-a-phenylnitrone is a commonly-used free radical trap. It contains radical scavenging activity and an ability to inhibit Cox-2 (cyclooxygenase-2). N-tert-Butyl-a-phenylnitrone is an antioxidant that has been shown to act as a protective agent in several experimental models of neurodegenerative disorders. N-tert-Butyl-a-phenylnitrone inhibits lipid peroxidation in rat liver microsomes. It also prevents the induction of inducible nitric oxide synthase (iNOS) by reactive oxygen species.

Solubility
Soluble in DMSO (10 mg/ml), chloroform (50 mg/ml), and water (20 mg/ml).

Notes
Store in a cool place. Reactive with oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 3376-24-7
• Molecular Formula: C11H15NO
• Molecular Weight (g/mol): 177.247
• MDL Number: MFCD00008799
• InChI Key: IYSYLWYGCWTJSG-FMIVXFBMSA-N
• Synonym: e-n-benzylidene-2-methylpropan-2-amine oxide
• PubChem CID: 10313352
• IUPAC Name: N-tert-butyl-1-phenylmethanimine oxide
• SMILES: CC(C)(C)[N+](=CC1=CC=CC=C1)[O-]

• Melting Point: 71°C to 75°C
• Quantity: 1 g
• Beilstein: 2044028
• Merck Index: 14,7056
• Solubility Information: Soluble in DMSO (10mg/ml),chloroform (50mg/ml),and water (20mg/ml).
• Formula Weight: 177.25
• Percent Purity: 98%
• Chemical Name or Material: N-tert-Butyl-alpha-phenylnitrone

Safety and Handling

EINECSNumber	222-168-6
TSCA	Yes
Recommended Storage	Keep cold

SDS

RUO – Research Use Only