N-(tert-Butyldimethylsilyl)-N-methyltrifluoroacetamide, 97%

Description

CAS: 77377-52-7 | C9H18F3NOSi | 241.329 g/mol

It finds its application in the preparation of N-tert-butyldimethylsilyl ethanolamines resulting from hydrolysis of nitrogen mustards and a silylating agent used in the derivatization of various organic compounds (such as amino acids) for gas chromatography-mass spectrometry (GC-MS) analysis and selective O-silylation of N,O-diacylhydroxylamines and GLC derivatization.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It finds its application in the preparation of N-tert-butyldimethylsilyl ethanolamines resulting from hydrolysis of nitrogen mustards and a silylating agent used in the derivatization of various organic compounds (such as amino acids) for gas chromatography-mass spectrometry (GC-MS) analysis and selective O-silylation of N,O-diacylhydroxylamines and GLC derivatization.

Solubility
Soluble in water (reacts).

Notes
Moisture sensitive. Store away from water/moisture and oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Store away from electrostatic charges. Keep ignition sources away.

Specifications

Chemical Identifiers

• CAS: 77377-52-7
• Molecular Formula: C9H18F3NOSi
• Molecular Weight (g/mol): 241.329
• MDL Number: MFCD00009671
• InChI Key: QRKUHYFDBWGLHJ-UHFFFAOYSA-N
• Synonym: mtbstfa, n-tert-butyldimethylsilyl-n-methyltrifluoroacetamide, n-methyl-n-tert-butyldimethylsilyl trifluoroacetamide, n-tert-butyldimethylsilyl-n-methyl-trifluoroacetamide, n-methyl-n-t-butyldimethylsilyl trifluoroacetamide, acetamide, n-1,1-dimethylethyl dimethylsilyl-2,2,2-trifluoro-n-methyl, n-t-butyldimethylsilyl-n-methyltrifluoroacetamide, n-t-butyldimethylsilyl-n-methyltrifluoro-acetamide
• PubChem CID: 2724275
• ChEBI: CHEBI:85060
• IUPAC Name: N-[tert-butyl(dimethyl)silyl]-2,2,2-trifluoro-N-methylacetamide
• SMILES: CC(C)(C)[Si](C)(C)N(C)C(=O)C(F)(F)F

• Density: 1.023
• Boiling Point: 168°C to 170°C
• Flash Point: 52°C (125°F)
• Refractive Index: 1.402
• Quantity: 25 g
• UN Number: UN1993
• Beilstein: 3606546
• Sensitivity: Moisture sensitive
• Solubility Information: Soluble in water (reacts).
• Formula Weight: 241.33
• Percent Purity: 97%
• Chemical Name or Material: N-(tert-Butyldimethylsilyl)-N-methyltrifluoroacetamide

Safety and Handling

Hazard Category	H226-H315-H319-H335
Hazard Statement	GHS H Statement H226-H315-H319-H335 Flammable liquid and vapour. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P210-P233-P235-P240-P241-P242-P243-P261-P264b-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P332+P313-P363-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 3; Packing Group: III; Proper Shipping Name: FLAMMABLE LIQUIDS, N.O.S.
EINECSNumber	000-000-0
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only