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Medchemexpress LLC N1-(4-chlorophenyl)-6-methyl-N5-[3-(9H-purin-6-yl)-2-pyridinyl]-1,5-isoquinolinediamine | 1093100-40-3 | MFCD22571725 | 98.0% | C26H19ClN8 | 10MG
SDP

Catalog No. 5000261229
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Raf inhibitor 1 is a potent small-molecule Raf kinase inhibitor that binds and stabilizes B-Raf in a DFG-out inactive conformation and suppresses proliferation in sensitive cancer cell lines such as A375 and HCT-116.

  • High potency against B-RafWT, B-RafV600E, and C-Raf (Ki: 1 nM, 1 nM, 0.3 nM).
  • High purity (98.03%) suitable for biochemical and cellular assays.
  • Solid form with good solubility in DMSO (50 mg/mL) for in vitro use.
  • Formulations available for in vivo dosing (clear or suspended solutions at ≥2.5 mg/mL).
  • Stable under recommended storage conditions for long-term use.

Catalog No. 50-002-61229 Supplier Medchemexpress LLC Supplier No. HY1417710MG
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Raf inhibitor 1 is a potent small-molecule Raf kinase inhibitor that binds and stabilizes B-Raf in a DFG-out inactive conformation and suppresses proliferation in sensitive cancer cell lines such as A375 and HCT-116.

  • High potency against B-RafWT, B-RafV600E, and C-Raf (Ki: 1 nM, 1 nM, 0.3 nM).
  • High purity (98.03%) suitable for biochemical and cellular assays.
  • Solid form with good solubility in DMSO (50 mg/mL) for in vitro use.
  • Formulations available for in vivo dosing (clear or suspended solutions at ≥2.5 mg/mL).
  • Stable under recommended storage conditions for long-term use.

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