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Medchemexpress LLC N2,N2-Dimethylguanosine | 2140-67-2 | 311.29 | 1 ML
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Supplier:  Medchemexpress LLC HY11313710MM/1ML

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N2,N2-Dimethylguanosine is a methylated nucleoside present in RNA and a structural modification component of tRNA. It hinders reverse transcriptase-mediated cDNA synthesis and affects sequencing efficiency in high-throughput RNA sequencing. It can be selectively demethylated by AlkB mutant enzymes into N2-methylguanosine, which reduces its hindrance to reverse transcription.

  • Methylated nucleoside present in RNA.
  • Structural modification component of tRNA.
  • Hinders reverse transcriptase-mediated cDNA synthesis.
  • Affects sequencing efficiency in high-throughput RNA sequencing.
  • Can be selectively demethylated by AlkB mutant enzymes.
  • Reduces hindrance to reverse transcription after conversion to N2-methylguanosine.

Catalog No. 50-004-37330


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