Medchemexpress LLC N2,N2-Dimethylguanosine | 2140-67-2 | 99.4% | 311.29 | 1 MG

Supplier:  Medchemexpress LLC HY1131371MG

N2,N2-Dimethylguanosine is a methylated nucleoside found in RNA and tRNA. It interferes with reverse transcriptase-mediated cDNA synthesis and impacts high-throughput RNA sequencing efficiency. The compound can be selectively demethylated by AlkB mutant enzymes into N2-methylguanosine, which helps to reduce reverse transcription hindrance.

• Methylated nucleoside present in RNA and tRNA.
• Hinders reverse transcriptase-mediated cDNA synthesis.
• Affects sequencing efficiency in high-throughput RNA sequencing.
• Can be converted to N2-methylguanosine by AlkB mutant enzymes to reduce reverse transcription hindrance.

Catalog No. 50-004-37749