Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC N2,N2-Dimethylguanosine | 2140-67-2 | 99.4% | 311.29 | 10 MG
Supplier: Medchemexpress LLC HY11313710MG
N2,N2-Dimethylguanosine is a methylated nucleoside found in RNA and is a structural modification component of tRNA. It hinders reverse transcriptase-mediated cDNA synthesis and is a key modification affecting sequencing efficiency in high-throughput RNA sequencing. It can selectively remove one methyl group through AlkB mutant enzymes (e.g., D135S/L118V) to convert into N2-methylguanosine, which reduces hindrance to reverse transcription.
- Methylated nucleoside present in RNA and tRNA.
- Hinders reverse transcriptase-mediated cDNA synthesis.
- Key modification affecting sequencing efficiency in high-throughput RNA sequencing.
- Can be selectively demethylated by AlkB mutant enzymes to N2-methylguanosine, reducing reverse transcription hindrance.
- For research use only.
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?