Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000211391

Medchemexpress LLC N3-PEG3-vc-PAB-MMAE | 99.1% | 1352.66 | C67H109N13O16 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY1008745MG

Encompass_Preferred

N3-PEG3-vc-PAB-MMAE is an azide-functionalized drug-linker for antibody-drug conjugate research that combines a PEG3 spacer, a valine-citrulline cleavable peptide with a p-aminobenzyl self-immolative spacer, and the cytotoxic payload monomethyl auristatin E (MMAE). It is designed for bioorthogonal conjugation and ADC construction, supplied as a white to off-white solid with high purity.

  • Azide-functionalized for CuAAC and SPAAC conjugation.
  • Peg3 spacer improves solubility and flexibility of conjugates.
  • Valine-citrulline-PAB linker enables enzymatic release of payload.
  • MMAE payload provides potent antimitotic activity.
  • High molecular weight (1352.66) supports defined stoichiometry in ADCs.
  • High purity (~99.1%) reduces impurities in conjugation reactions.
  • Powder stable at -20°C (3 years) and 4°C (2 years); prepare fresh in solution.

Catalog No. 50-002-11391


May include imposed supplier surcharges.
Only null left
Add to Cart

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.