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Medchemexpress LLC N4-((1H-pyrazol-3-yl)methyl)-N2-(2-methyl-1,2,3,4-tetrahydroisoquinolin-6-yl)-5-(trifluoromethyl)pyr | 2623158-64-3 | 99.5% | C19H20F3N7 | 10MG
SDP

Supplier:  Medchemexpress LLC HY13960410MG

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PCC0208017 is a potent, selective small-molecule inhibitor of microtubule affinity-regulating kinases MARK3 and MARK4 developed for preclinical research. It displays low-nanomolar biochemical potency and has shown cellular and in vivo activity in glioma models. The compound is supplied as an off-white to light-yellow solid and is available in solid and DMSO solution formats suitable for screening and pharmacology studies.

  • Potent MARK3 and MARK4 inhibition (IC50 1.8 nM and 2.01 nM).
  • Reduced activity against MARK1 and MARK2 enabling selectivity profiling.
  • High purity suitable for biochemical assays (≈99.5%).
  • Available as solid and as pre-made DMSO solution for flexible use.
  • Off-white to light-yellow solid form for easy handling and formulation.
  • Supplied with batch certificate of analysis for traceable quality.

Catalog No. 50-002-60256


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