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Medchemexpress LLC N4-(4-(dimethylamino)phenyl)-2-(pyridin-4-yl)-5,6,7,8-tetrahydroquinazoline-4,6-diamine | 2230854-93-8 | 98.1% | C21H24N6 | 10MG

Supplier: Medchemexpress LLC HY13746610MG
ARN-21934 is a selective small-molecule inhibitor of human topoisomerase IIα with reported blood-brain barrier penetration and favorable in vivo pharmacokinetics. It inhibits DNA relaxation (IC50 = 2 μM versus etoposide 120 μM) and is supplied for research use only.
- Selective topoisomerase IIα inhibition (IC50 = 2 μM).
- Reported blood-brain barrier penetration and favorable in vivo profile.
- Molecular formula C21H24N6; molecular weight 360.46 g·mol⁻¹.
- High purity, 98.1%.
- Available as solid (5-100 mg) and 10 mM solution in DMSO (1 mL).
- Intended for laboratory research use; not for human use.
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