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Cayman Chemical N6-CyclohexyladenosIn 100mg
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Supplier:  Cayman Chemical 28427100 MG

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An adenosine receptor agonist; selectively binds to adenosine A1 receptors in rat cortical membranes (IC50 = 2.3 nM) over A2 receptors in rat striatal membranes (IC50 = 870 nM); decreases heart rate and increases coronary flow in a perfused working rat heart model ex vivo (EC25s = 5 and 860 nM, respectively); decreases heart rate and blood pressure in normotensive rats in vivo (EC25s = 2.4 and 4.2 μg/kg, respectively); induces sleep in rats via basal forebrain infusion at 100 μM; decreases locomotor activity in mice (ED50 = 60 μg/kg, i.p.)

Catalog No. 50-293-9094


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