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Cayman Chemical -nabasInhydrochlorIde 50mg
Supplier: Cayman Chemical 1820650 MG
An alkaloid agonist of nAChRs with teratogenic activity; induces depolarization of TE 671 cells endogenously expressing human fetal muscle-type nAChRs (EC50 = 10.1 µM); binds to α4β2 subunit-containing nAChRs in K177 cells (Ki = 37.63 nM); teratogenic in vivo, inducing congenital defects, including cleft palate and severe fixed excessive flexure of carpal joints, in piglets when administered to pregnant dams during gestation days 43-53 at a dose of 2.6 mg/kg twice per day
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