Cayman Chemical NADIFLOXACIN 100MG

Supplier:  Cayman Chemical 20252100 MG

A fluoroquinolone antibiotic; active against clinical isolates of S. aureus, coagulase-negative staphylococci, P. acnes, and P. granulosum (MIC50s = 0.03, 0.06, 0.25, and 0.125 mg/L, respectively); inhibits the activities of DNA gyrase and topoisomerase IV (IC50s = 8.83 and 3.22 mg/L, respectively, for the S. aureus enzymes); inhibits P. acnes-induced increases in the production of IFN-γ, IL-1β, and IL-12p70 in human PBMCs, as well as reduces P. acnes-induced increases in the production of IL-8 and IL-6 in isolated human keratinocytes; reduces the number of skin lesion CFUs in a mouse model of burn wounds infected with S. aureus or P. acnes when applied topically as a cream at 1%

Catalog No. 50-298-5324