AdipoGen NADK M tuberculosis His

Supplier:  AdipoGen AG40T0107C050

Protein. NAD kinase Mycobacterium tuberculosis is fused at the N-terminus to a His-tag. Source E. coli. Endotoxin content N/A. Liquid. In 10mM TRIS at pH 8.0, containing 1mM MgCl2, 0.5mM EDTA, 1mM DTT and 1mM PMSF. Purity >98% SDS-PAGE. NAD kinase catalyzes the transfer of a phosphate group from ATP to NAD to generate NADP, which in its reduced form acts as an electron donor for biosynthetic reactions. NADP is an essential coenzyme in metabolism and provides reducing power to biosynthetic processes such as fatty acid biosynthesis. NAD kinase from Mycobacterium tuberculosis is not ATP-dependent but has a broader substrate specificity than human NAD kinase. It can economically produce NADP by using other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Was identified as a high-confidence drug target. Catalytic activity ATP NAD = ADP NADP

Catalog No. 50-256-2760