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Medchemexpress LLC Nafamostat mesylate | 82956-11-4 | 99.9% | 500 MG
Supplier: Medchemexpress LLC HYB0190A500MG
Nafamostat mesylate (FUT-175) is an anticoagulant and a synthetic serine protease inhibitor. It demonstrates anticancer and antiviral effects by inducing apoptosis through up-regulating the expression of tumor necrosis factor receptor-1 (TNFR1). This compound is also being investigated for its use in addressing the pathological thickening of the arterial wall.
- Acts as an anticoagulant and synthetic serine protease inhibitor
- Demonstrates anticancer and antiviral effects
- Induces apoptosis via TNFR1 up-regulation
- Investigated for treating pathological arterial wall thickening
- Inhibits NF-κB activity and IκBα phosphorylation
- Suppresses invasiveness in specific cell lines
- Exhibits inhibitory effects on neointimal formation in animal models
- Provides antiviral benefits against Zika virus in animal models
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