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TARGETMOL CHEMICALS INC Naftifine hydrochloride 1G
Supplier: TARGETMOL CHEMICALS INC T15431G
Also available in 1 mL, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Naftifine Hydrochloride is the hydrochloride salt form of naftifine, an allylamine derivate with synthetic broad-spectrum antifungal activity. Although the exact mechanism through which naftifine hydrochloride exerts its effect is unknown, it appears to selectively inhibit the enzyme squalene 2, 3-epoxidase, thereby inhibiting the biosynthesis of sterol. This results in a decreased amount of sterols, especially ergosterol which is the primary fungal membrane sterol, and a corresponding accumulation of squalene in fungal cells. Naftifine hydrochloride (Naftifine HCl) can be fungicidal as well as fungistatic to yeasts depending on the concentration and the organisms involved. Purity 99.76%
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