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AdipoGen NAI-97 Planosporicin
SDP

Supplier:  AdipoGen AGCN20312M001

Encompass_Preferred

Chemical. CAS 802917-82-4. Formula C90H125N27O28S5. MW 2193.5. Isolated from Planomonospora sp. Antibacterial class I lantibiotic. Inhibits cell wall synthesis and consequently bacterial growth by forming a complex with lipid intermediate II Lipid II, a key intermediate in peptidoglycan biosynthesis. Interfers with late stages of cell wall biosynthesis leading to accumulation of the soluble peptidoglycan precursor UDP-N-acetylmuramic acid-pentapeptide UDP-MurNAc-pentapeptide in the cytoplasm less efficient than NAI-107. Active against aerobic and anaerobic Gram-positive pathogens, including all antibiotic-resistant strains e.g. MRSA and VRE in whole cell and in vitro assays as well as in vivo.

Catalog No. 50-256-2612


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