Nalidixic acid, 99%

Description

CAS: 389-08-2 | C12H12N2O3 | 232.239 g/mol

Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent. It is also used as an inhibitor of bacterial DNA gyrase. It plays an important role in the treatment of urinary tract infections caused by susceptible gram-negative microorganisms, including the majority of E. Coli, Enterobacter species, Klebsiella species and Proteus species.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent. It is also used as an inhibitor of bacterial DNA gyrase. It plays an important role in the treatment of urinary tract infections caused by susceptible gram-negative microorganisms, including the majority of E. Coli, Enterobacter species, Klebsiella species and Proteus species.

Solubility
Soluble in diethyl ether, acetone, methylene chloride, chloroform and methanol. Insoluble in water.

Notes
Light sensitive and air sensitive. Store in a cool place. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 389-08-2
• Molecular Formula: C12H12N2O3
• Molecular Weight (g/mol): 232.239
• MDL Number: MFCD00006884
• InChI Key: MHWLWQUZZRMNGJ-UHFFFAOYSA-N
• Synonym: nalidixic acid, nalidixin, nevigramon, nalidixate, uronidix, innoxalon, nalidixan, nalitucsan, sicmylon, unaserus
• PubChem CID: 4421
• ChEBI: CHEBI:100147
• IUPAC Name: 1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid
• SMILES: CCN1C=C(C(=O)C2=C1N=C(C=C2)C)C(=O)O

• Melting Point: 228°C to 230°C
• Quantity: 5 g
• Beilstein: 750515
• Merck Index: 14,6359
• Solubility Information: Soluble in diethyl ether,acetone,methylene chloride,chloroform and methanol. Insoluble in water.
• Formula Weight: 232.24
• Percent Purity: 99%
• Chemical Name or Material: Nalidixic acid

Safety and Handling

Hazard Category	H317-H334-H336-H341
Hazard Statement	GHS H Statement H302 Harmful if swallowed.
Precautionary Statement	P261-P272-P280g-P285-P302+P352-P304+P341-P333+P313-P342+P311-P363-P501c
EINECSNumber	206-864-7
RTECSNumber	QN2885000
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only