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Cayman Chemical NalmefenhydrochlorIde 50mg
Supplier: Cayman Chemical 2826650 MG
A μ- and κ-opioid receptor antagonist (Kis = 0.91 and 1.03 nM, respectively, in CHO membranes expressing the human receptors); selective for μ- and κ-opioid receptors over δ-opioid receptors (Ki = 13.26 nM in CHO membranes expressing the human receptors); decreases self-administration of alcohol in non-alcohol- and alcohol-dependent rats; reduces food and water intake and body weight in obese and lean rats at 25 mg/kg per day; inhibits morphine-induced scratching behavior and increases in the latency to tail withdrawal in a warm water tail withdrawal assay in rhesus monkeys at 32 UG/kg
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