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Medchemexpress LLC Naloxegol oxalate | 1354744-91-4 | 99.9% | C36H55NO15 | 5 MG
Supplier: Medchemexpress LLC HYA0118A5MG
Naloxegol oxalate is an orally active, peripherally acting μ-opioid receptor antagonist (target Ki 7.42 nmol/L). It inhibits opioid binding to gastrointestinal μ-opioid receptors, alleviating opioid-induced gastrointestinal hypomotility, delayed transit, hypertonicity, and increased fluid reabsorption. It is applicable for research into opioid-induced constipation.
- Orally active
- Peripherally acting μ-opioid receptor antagonist
- Inhibits opioid binding to gastrointestinal μ-opioid receptors
- Alleviates opioid-induced gastrointestinal hypomotility and related issues
- Applicable to research on opioid-induced constipation
- High affinity binding to μ and κ-opioid receptors in vitro
- Low affinity to δ-opioid receptors in vitro
- No significant activity at non-opioid targets in vitro
- Available in solid and solution forms
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