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Medchemexpress LLC Naloxegol oxalate | 1354744-91-4 | 99.91% | C36H55NO15 | 100 MG
Supplier: Medchemexpress LLC HYA0118A100MG
Naloxegol oxalate is an orally active, peripherally acting μ-opioid receptor antagonist. It inhibits the binding of opioids to μ-opioid receptors in the gastrointestinal tract, alleviating opioid-induced gastrointestinal hypomotility, delayed transit, hypertonicity, and increased fluid reabsorption. It is used in research related to opioid-induced constipation.
- Binds with high affinity to μ-opioid and κ-opioid receptors
- Exhibits low affinity to δ-opioid receptors in vitro
- Shows no significant activity at non-opioid targets
- Alleviates opioid-induced slowed gastrointestinal motility and transit
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